Engineering and Technology: Bioengineering, Medical Physics: Radiation Oncology, Physics: Optics and Laser
Multiple postdoctoral positions are available in the Division of Medical Physics in the Department of Radiation Oncology at Johns Hopkins Hospital. The candidate will be tasked to advance pre-clinical 3D optical-guided radiation therapy (RT), specifically, the development of a quantitative bioluminescence (BLT) and fluorescence tomography (FT)/x-ray cone beam CT (CBCT) system for pre-clinical radiation research. The tri-modality (BLT/FT/CBCT) imaging system is expected to localize tumor in vivo, guide radiation, and quantify the tumor response to cancer therapy.
The project has a strong translation component. The postdoctoral fellows will work closely with the principal investigator Dr. Ken Wang, the industrial partner Xstrahl Inc, and other academic partners in translating the research development to the scientific community. The candidate will play a key role in the development of the advanced optical tomography system, reconstruction algorithms, and performing system validation with advanced orthotopic and spontaneous tumor models. The project is supported by long term NIH R01 grants (Academic-Industrial Partnership and Bioengineering Research Grant), R21 grant as well as industrial funding. There are about 600 researchers utilizing pre-clinical irradiators for research investigation. The success of this project would provide next quantum leap for in vivo tumor identification in pre-clinical radiation research.
Independent problem solving, demonstrated publication record, strong verbal and written communication skills are must for this position.
The project has strong ties to human radiation medicine in terms of biomedical optics and image-guided radiation therapy. The position exposes the candidate to the practice of medical physics where he/she will have opportunities to receive clinical training and participate in selected tasks under the supervision of qualified medical physicists. The experience and knowledge gained from this project will prepare the candidate for the career paths for academic faculty, industrial position as well as medical physics residency.
Qualified applicants should have a recent PhD in biomedical engineering, physics, optics, medical physics or related discipline. Recent PhD graduates with experience in tissue optics, laser instrumentation, and animal model are encouraged to apply.
Interested candidates should send a cover letter, CV, and the names (with e-mail and phone contact information) of 3 academic references to Dr. Ken Wang at email address firstname.lastname@example.org
About Johns Hopkins University
The Department of Radiation Oncology at Johns Hopkins Hospital occupies 27,405 gross sq. ft, which includes laboratory and office space for the Division of Medical Physics. The department has one helical Tomotherapy unit capable of megavoltage CT guided radiation therapy. Six medical accelerators with cone beam CT imaging for guidance and with multileaf collimators are used to deliver intensity or volumetric modulated radiation treatment. Stereotactic radiosurgery procedures are performed on an Accuracy Cyberknife system. Patient volumetric imaging data are acquired on two Philips Brilliance big bore CT system with 4D CT capability and a Siemens Eclipse 1.5T MRI.///
The Johns Hopkins’ biomedical cancer research program, the Sidney Kimmel Comprehensive Cancer Center (SKCCC) at the medical campus, was first established in the 1970’s as part of Johns Hopkins’ NCI designated comprehensive cancer center. The major body of SKCCC research is currently housed in two state of the art research buildings, the Bunting Blaustein Cancer Research Building (CRB1) and the David H. Koch Cancer Research Building (CRB2). Each building houses 5 floors of dedicated laboratory space and offices (54...0,000 sq. ft). This environment provides working space for over 800 researchers and staff. These two buildings are connected by a 250-seat auditorium that fosters an interdisciplinary environment in which cancer scientists are brought together from a variety of departments.///
Dr. Ken Wang’s laboratory operates in the SKCCC. The lab is located on the lower basement of CRB2, a state-of-the-art, newly constructed building entirely dedicated to research and teaching. The total lab space area is 600 sq. ft, with additional joint lab resources of 2900 sq. ft. The lab is fully equipped for optical bench, light tight housing, integrating sphere, light sources, and other instruments for quantitative optical analysis. Dr. Wang’s lab also houses the small animal radiation research platform (SARRP) and bioluminescence tomography (BLT) systems.
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