Molecular Assay Scientist

Employer
Synectics Inc
Location
Cambridge, Massachusetts
Salary
Commensurate
Posted
Jan 15, 2025
Closes
Feb 07, 2025
Ref
2881097751
Discipline
Physics, Atomic & Molecular Physics, Engineering & Applied Science, Robotics, Manufacturing & Instrumentation
Role Type
Scientist
Career Level
Experienced Career
Education
Bachelor
Work Mode
Onsite
Contract Type
Full Time
Organization Type
Commercial / Industry
Description :
  • Will work with a talented and experienced team in our Technical Research and Development organization at Cambridge, Massachusetts.
  • Will be an important point of contact for the coordination and execution of molecular, potency and characterization assays, qualification studies, and method transfer activities within area of expertise.
  • Will interface regularly and build relationships with other functions such as Process Development, Quality Control and Manufacturing Sciences & Technology to collaboratively drive projects to meet the established timelines while maintaining the highest quality and data integrity standards.
  • Will uphold company Values & Beliefs and Code of Ethics to successfully support our bold mission of delivering effective CAR-T cell products for patients in need.
  • Perform analytical testing including flow cytometry, cell count, cell viability, qPCR/dPCR, potency, etc. following appropriate SOPs and procedures.
  • Review and approve data by other team members.
  • Record and maintain meticulous records in electronic laboratory notebook in compliance with Quality standards
  • Identifies opportunities for method improvement
  • Execute qualification/optimization of analytical methods
  • Drive project timelines and deliverables while meeting internal quality and data integrity requirements
  • Communicate effectively and present complex data within the department and cross-functionally
  • Author and review method related technical documents to ensure completeness, accuracy, consistency and clarity
  • Support tracking and trending systems, and programs, which assist in the testing, evaluation and monitoring of quality and efficiency
  • Serves as a technical associate expert to support analytical testing and implementation of novel analytical methodologies for our CAR-T cell therapy products.

Requirements :
  • BA/BS or MS in biology, chemistry, biochemistry, microbiology or other related science + 1 year of prior experience in industry or academia.
  • Understanding of the basic scientific principles underpinning the analytical methods such as flow cytometry, PCR, ELISA, cell-based assays
  • Expertise with aseptic technique and mammalian cell culture, Human T-cell culture experience a plus
  • Ability to communicate clearly with internal or cross-functional teams
  • Detail-oriented with expertise in problem solving & demonstrated ability to work in a team environment
  • Established ability to work in a regulated environment
  • Good presentation skills and scientific/technical writing skills
  • Experience writing laboratory SOPs and technical instructions is preferred
  • 0-4 years of experience in pharmaceutical, biologics industry
  • Understanding of the concepts of cGxP.
  • Strong written and verbal communication skills are essential

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